A study on the convergence of observer-based kinetics estimators in stirred tank bioreactors
نویسندگان
چکیده
This paper is devoted to the tuning problem of an observer-based algorithm for the on-line estimation of reaction rates in stirred tank bioreactors. The relation between the dynamics of convergence and the tuning procedure is explored. The method proposed imposes a variable second-order dynamics on the convergence of the estimator. This approach is shown to compare favourably with a pole placement based technique, in an application to a baker's yeast fed-batch fermentation. Copyright 1996 Published by Elsevier Science Ltd
منابع مشابه
Adaptive Extremum Seeking Control of Continuous Stirred Tank Bioreactors
In this paper, we present an adaptive extremum seeking control scheme for continuous stirred tank bioreactors. The proposed adaptive extremum seeking approach utilizes the structure information of the kinetics of the bioreactors to construct a seeking algorithm that drives the system states to the desired set-points that extremize the value of an objective function. Lyapunov’s stability theorem...
متن کاملAdaptive extremum seeking control of continuous stirred tank bioreactors with unknown growth kinetics
In this paper, we present an adaptive extremum seeking control scheme for continuous stirred tank bioreactors. We assume limited knowledge of the growth kinetics. An adaptive learning technique is introduced to construct a seeking algorithm that drives the system states to the desired set-points that maximizes the value of an objective function. Lyapunov’s stability theorem is used in the desig...
متن کاملCell Culture Bioreactors
Cell Culture Bioreactors Basic Types of Bioreactors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1 Stirred Tank (Well Mixed) vs. Tubular Reactor (Plug Flow) . . . . . . . . . . . . . . . . . 3 Segregated Bioreactors (Dead Zone Present) Compartmentalized Bioreactors . . 4 Implication When Growth or Reaction Occurs in the Reactor . . . . . ....
متن کاملبررسی راندمان بیوراکتور دو فازی همزن دار به منظور تصفیه بخارات گزیلن از جریان هوا با بستری از سودوموناس پتیدا
Introduction: Volatile organic compounds such as xylene, which are the main constituents of the oil and petrochemical industries, have serious impacts on health and can cause adverse effects on the environment. It is clear that release of these compounds into the environment should be controlled. The two-phases partitioning stirred tank bio-reactor is one of the newest methods for treating thes...
متن کاملHigh cell density cultivation of recombinant yeasts and bacteria under non-pressurized and pressurized conditions in stirred tank bioreactors.
This study demonstrates the applicability of pressurized stirred tank bioreactors for oxygen transfer enhancement in aerobic cultivation processes. The specific power input and the reactor pressure was employed as process variable. As model organism Escherichia coli, Arxula adeninivorans, Saccharomyces cerevisiae and Corynebacterium glutamicum were cultivated to high cell densities. By applying...
متن کامل